I am positive, my partner is negative and we practice safe sex. So I figured you would be the guy to ask this one. Rob I am a true fan of yours and always appreciate your candor and sense of humor. Remember not to use them if you take erectile dysfunction drugs (Viagra, Cialis, etc.), because combined they can cause a dangerous drop in blood pressure. I'll post some information below from the archives regarding poppers. They can dilate blood vessels, but that doesn't necessarily increase your risk of acquiring HIV from receptive oral sex. Thanks again.just trying to remain as safe as possible! Answer